Xenium delivers industry-leading speed and throughput through multimodal cell segmentation, analyzing 472 mm² of tissue per run, targeting up to 480 genes in <3 days or up to 5000 genes in <6 days. This instrument enables spatial, single-cell-scale gene expression analysis of preselected or customizable RNA molecules from tissue sections, while also enabling co-visualization of IF and H&E on the same section.